2017

Gollner, S., Oellerich, T., Agrawal-Singh, S., Schenk, T., Klein, H.U., Rohde, C., Pabst, C., Sauer, T., Lerdrup, M., Tavor, S., Stolzel, F., Herold, S., Ehninger, G., Kohler, G., Pan, K.T., Urlaub, H., Serve, H., Dugas, M., Spiekermann, K., Vick, B., Jeremias, I., Berdel, W.E., Hansen, K., Zelent, A., Wickenhauser, C., Muller, L.P., Thiede, C. & Muller-Tidow, C. (2017) Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia. Nat Med, 23, 69-78.

Gebler, C., Lohoff, T., Paszkowski-Rogacz, M., Mircetic, J., Chakraborty, D., Camgoz, A., Hamann, M.V., Theis, M., Thiede, C. & Buchholz, F. (2017) Inactivation of Cancer Mutations Utilizing CRISPR/Cas9. J Natl Cancer Inst, 109.

Strickland, M.R., Gill, C.M., Nayyar, N., D'Andrea, M.R., Thiede, C., Juratli, T.A., Schackert, G., Borger, D.R., Santagata, S., Frosch, M.P., Cahill, D.P., Brastianos, P.K. & Barker, F.G., 2nd (2017) Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas. J Neurosurg, 127, 438-444.

Stone, R.M., Mandrekar, S.J., Sanford, B.L., Laumann, K., Geyer, S., Bloomfield, C.D., Thiede, C., Prior, T.W., Dohner, K., Marcucci, G., Lo-Coco, F., Klisovic, R.B., Wei, A., Sierra, J., Sanz, M.A., Brandwein, J.M., de Witte, T., Niederwieser, D., Appelbaum, F.R., Medeiros, B.C., Tallman, M.S., Krauter, J., Schlenk, R.F., Ganser, A., Serve, H., Ehninger, G., Amadori, S., Larson, R.A. & Dohner, H. (2017) Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation. N Engl J Med, 377, 454-464.

Stolzel, F., Brosch, M., Horvath, S., Kramer, M., Thiede, C., von Bonin, M., Ammerpohl, O., Middeke, M., Schetelig, J., Ehninger, G., Hampe, J. & Bornhauser, M. (2017) Dynamics of epigenetic age following hematopoietic stem cell transplantation. Haematologica, 102, e321-e323.

Stefanko, A., Thiede, C., Ehninger, G., Simons, K. & Grzybek, M. (2017) Lipidomic approach for stratification of acute myeloid leukemia patients. PLoS One, 12, e0168781.

Silva, P., Neumann, M., Schroeder, M.P., Vosberg, S., Schlee, C., Isaakidis, K., Ortiz-Tanchez, J., Fransecky, L.R., Hartung, T., Turkmen, S., Graf, A., Krebs, S., Blum, H., Muller-Tidow, C., Thiede, C., Ehninger, G., Serve, H., Hecht, J., Berdel, W.E., Greif, P.A., Rollig, C. & Baldus, C.D. (2017) Acute myeloid leukemia in the elderly is characterized by a distinct genetic and epigenetic landscape. Leukemia, 31, 1640-1644.

Proschmann, R., Baldow, C., Rothe, T., Suttorp, M., Thiede, C., Tauer, J.T., Muller, M.C., Hochhaus, A., Roeder, I. & Glauche, I. (2017) Response dynamics of pediatric patients with chronic myeloid leukemia on imatinib therapy. Haematologica, 102, e39-e42.

Platzbecker, U., Avvisati, G., Cicconi, L., Thiede, C., Paoloni, F., Vignetti, M., Ferrara, F., Divona, M., Albano, F., Efficace, F., Fazi, P., Sborgia, M., Di Bona, E., Breccia, M., Borlenghi, E., Cairoli, R., Rambaldi, A., Melillo, L., La Nasa, G., Fiedler, W., Brossart, P., Hertenstein, B., Salih, H.R., Wattad, M., Lubbert, M., Brandts, C.H., Hanel, M., Rollig, C., Schmitz, N., Link, H., Frairia, C., Pogliani, E.M., Fozza, C., D'Arco, A.M., Di Renzo, N., Cortelezzi, A., Fabbiano, F., Dohner, K., Ganser, A., Dohner, H., Amadori, S., Mandelli, F., Ehninger, G., Schlenk, R.F. & Lo-Coco, F. (2017) Improved Outcomes With Retinoic Acid and Arsenic Trioxide Compared With Retinoic Acid and Chemotherapy in Non-High-Risk Acute Promyelocytic Leukemia: Final Results of the Randomized Italian-German APL0406 Trial. J Clin Oncol, 35, 605-612.

Middeke, J.M., Herbst, R., Parmentier, S., Bug, G., Hanel, M., Stuhler, G., Schafer-Eckart, K., Rosler, W., Klein, S., Bethge, W., Bitz, U., Buttner, B., Knoth, H., Alakel, N., Schaich, M., Morgner, A., Kramer, M., Sockel, K., von Bonin, M., Stolzel, F., Platzbecker, U., Rollig, C., Thiede, C., Ehninger, G., Bornhauser, M. & Schetelig, J. (2017) Long-Term Follow-Up and Impact of Comorbidity before Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Relapsed or Refractory Acute Myeloid Leukemia-Lessons Learned from the Prospective BRIDGE Trial. Biol Blood Marrow Transplant, 23, 1491-1497.

Lal, R., Lind, K., Heitzer, E., Ulz, P., Aubell, K., Kashofer, K., Middeke, J.M., Thiede, C., Schulz, E., Rosenberger, A., Hofer, S., Feilhauer, B., Rinner, B., Svendova, V., Schimek, M.G., Rucker, F.G., Hoefler, G., Dohner, K., Zebisch, A., Wolfler, A. & Sill, H. (2017) Somatic TP53 mutations characterize preleukemic stem cells in acute myeloid leukemia. Blood, 129, 2587-2591.

Kayser, S., Krzykalla, J., Elliott, M.A., Norsworthy, K., Gonzales, P., Hills, R.K., Baer, M.R., Racil, Z., Mayer, J., Novak, J., Zak, P., Szotkowski, T., Grimwade, D., Russell, N.H., Walter, R.B., Estey, E.H., Westermann, J., Gorner, M., Benner, A., Kramer, A., Smith, B.D., Burnett, A.K., Thiede, C., Rollig, C., Ho, A.D., Ehninger, G., Schlenk, R.F., Tallman, M.S., Levis, M.J. & Platzbecker, U. (2017) Characteristics and outcome of patients with therapy-related acute promyelocytic leukemia front-line treated with or without arsenic trioxide. Leukemia, 31, 2347-2354.

Heuser, M., Gabdoulline, R., Loffeld, P., Dobbernack, V., Kreimeyer, H., Pankratz, M., Flintrop, M., Liebich, A., Klesse, S., Panagiota, V., Stadler, M., Wichmann, M., Shahswar, R., Platzbecker, U., Thiede, C., Schroeder, T., Kobbe, G., Geffers, R., Schlegelberger, B., Gohring, G., Kreipe, H.H., Germing, U., Ganser, A., Kroger, N., Koenecke, C. & Thol, F. (2017) Individual outcome prediction for myelodysplastic syndrome (MDS) and secondary acute myeloid leukemia from MDS after allogeneic hematopoietic cell transplantation. Ann Hematol, 96, 1361-1372.

Herold, S., Sockel, K., Sayehli, C., Herbst, R., Duhrsen, U., Oelschlagel, U., Bottner, A., Hindahl, H., Kullmer, J., Helas, S., Sauer, M., Mohr, B., Mies, A., Bornhauser, M., Ehninger, G., Rollig, C., Thiede, C. & Platzbecker, U. (2017) Evolution of NPM1-negative therapy-related myelodysplastic syndromes following curative treatment of NPM1-mutant AML. Leukemia, 31, 2247-2251.

Herold, S., Kuhn, M., Bonin, M.V., Stange, T., Platzbecker, U., Radke, J., Lange, T., Sockel, K., Gutsche, K., Schetelig, J., Rollig, C., Schuster, C., Roeder, I., Dahl, A., Mohr, B., Serve, H., Brandts, C., Ehninger, G., Bornhauser, M. & Thiede, C. (2017) Donor cell leukemia: evidence for multiple preleukemic clones and parallel long term clonal evolution in donor and recipient. Leukemia, 31, 1637-1640.

Bochtler, T., Granzow, M., Stolzel, F., Kunz, C., Mohr, B., Kartal-Kaess, M., Hinderhofer, K., Heilig, C.E., Kramer, M., Thiede, C., Endris, V., Kirchner, M., Stenzinger, A., Benner, A., Bornhauser, M., Ehninger, G., Ho, A.D., Jauch, A., Kramer, A. & Study Alliance Leukemia, I. (2017) Marker chromosomes can arise from chromothripsis and predict adverse prognosis in acute myeloid leukemia. Blood, 129, 1333-1342.